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doi: 10.1016/j.phymed.2025.156873 134 Del CuoreAPipitoneRMCasuccioAMazzolaMMPuleoMGPacinellaGet al

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Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis

6 Conclusion and future perspectives In the past decades, statins, traditionally used because of their cholesterol-lowering properties, have demonstrated multifaceted effects on the immune system in general cellular homeostasis, including modulation of T cell responses and anti-inflammatory properties