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Nature 414 , 799806 (2001)

Front Psychiatry 10 , 97 (2019)

A combination of three laser devices was used to treat the pigmentation and acne scarring on this patients face

Common Side Effects When side effects occurred, they were typically mild, transient, and similar in frequency to placebo groups: Reported Adverse Effects Most Common (occurring in small percentage of participants): Mild to moderate headaches (most frequently reported, often resolving with continued use) Injection site reactions (minor redness, swelling, or irritation at injection site) Gastrointestinal effects (particularly at higher oral doses: mild nausea, diarrhea, flatulence) Fatigue (reported occasionally during initial adaptation period) Rare Events: One case of chest tightness was deemed possibly related to treatment in safety trials

( h ) BRCA1 mRNA expression (n = 3