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CLL cells had decreased sensitivity to the ROS inducing agents fludarabine and oxiplatin when co-cultured with BM stromal cells.9 Chemo-protection was derived from the generation and release of cysteine by stromal cells for uptake by CLL cells

Rather than inheriting one gene which, in a dominant fashion, would induce GD, individuals inherit many different genetic polymorphisms which are conducive to the development of AITD (115-117)

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By regulating the activation of these transcription factors, TQ can counteract different tumorigenic processes including inflammation, cell proliferation, cell survival, angiogenesis, cell invasions, and metastasis

10.1074/jbc.M116.762567 J