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Common Causes of B12 Deficiency Document the cause of B12 deficiency to support the specific code : Pernicious anemia Autoimmune destruction of stomach cells Gastrectomy or weight loss surgery Loss of intrinsic factor production Strict vegetarian diet Inadequate dietary intake Crohns disease or celiac disease Malabsorption in the small intestine Chronic pancreatitis Insufficient pancreatic enzymes Bacterial overgrowth in the small intestine Bacteria consume B12 Long-term metformin use Interferes with B12 absorption Neurologic Symptoms in B12 Deficiency B12 deficiency causes nerve damage
Damage to the myelin sheath is why patients with pernicious anemia and B12 deficiency often report having pins and needles and other nerve-related sensations
In some research contexts, observations have included mild and transient tolerability-related effects such as: Headaches Nausea Stimulation-related observations Temporary injection-site irritation or localized skin-response variability Research conditions, concentration ranges, dosage ranges, hydration status, administration frequency, and protocol structure may influence tolerability observations across experimental settings
