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The presence of babA , cagA and vacAs1 , referred to as the "triple positive strains" may be associated with duodenal ulcer or gastric adenocarcinoma in Western populations (56)

doi: 10.1128/JVI.01245-08

In aortic smooth muscle cells, it has been found that the disintegrin echistatin or blocking antibodies to v3 integrin blocked IGF-1-stimulated proliferation, IGF-1R autophosphorylation, IRS-1 phosphorylation, and binding of the p85 subunit of PI3K to IRS-1

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& Upcroft, J