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Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene

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Copper deficiency myelopathy is more likely to occur in patients who have undergone upper gastrointestinal surgery, typically between the ages of 50 and 60 years, and is more common in women than in men

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Its design illustrates a radical peptidomimetic : only two amino acid residues (Tyr-Ile) are preserved from the native peptide, flanked by non-peptide acyl chains to cross biological barriers

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