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In view of the findings in the British inhalation study, however, Avram maintains that the burden of proof has shifted and its now up to them (clove cigarette critics) to prove there is a problem with clove cigarettes instead of clove cigarettes being put on the defensive. Robert Phalen, director of the air pollution health effects laboratory at the College of Medicine at UC Irvine and author of Inhalation Studies, a professional reference book, observed that the inhalation study is important, but Id say a single study is not definitive for something that has widespread use. Phalen added that theres a segment of the population--somewhere around 5%--that have very sensitive lungs