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Phase II Clinical Data Jastreboff 2023 (NEJM) reported 24.2% bodyweight reduction at 48 weeks - the largest effect size published for any metabolic peptide in clinical trials

Not intended for injection in humans or animals outside of controlled laboratory settings

Journal of Physiology and Pharmacology, 64(5), 597-612

By midlife, NAD+ can drop by 50%, exacerbated by inflammation and lifestyle.[14] Factors like poor diet, sedentary behavior, or chronic stress further deplete NAD+ by activating consuming enzymes, creating a vicious cycle

For systemic research, it must be administered via subcutaneous or intramuscular injection to bypass the digestive tract and ensure bioavailability