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It helps reduce hyperpigmentation, boosts collagen production, and contributes to a more youthful complexion

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They also found that knocking down P300 inhibited the enrichment of H3K27ac in three regions of the STEAP3 gene, thus significantly reducing the expression of the STEAP3 gene and accompanying a phenotype of inhibited cell proliferation

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In mice, the loss of JNK1 and JNK2 led to more severe age-related OA and ageing of cartilage and synovium (Loeser et al., 2020), an indication that JNK is a detrimental regulator of joint degeneration