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For clinic review, call if you notice: Increasing pain and spreading redness beyond the immediate area after 48 to 72 hours

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A brief neurological exam to rule out an occult neurologic problem and an evaluation for incomplete bladder emptying to rule out occult retention should be done on all patients

Rational design is not widely used, except for P5, PRG-RADA16, and RK81 QTY [97,130]

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