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Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway

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Unlike pepsin, a well-known gastric Asp protease that cannot break down these Pro-rich gluten peptides, RmuAP1CD appears to tolerate Pro residues near the scissile bonds, the specific peptide bonds targeted and cleaved by proteases (Ali et al

Exosomes derived from vascular endothelial cells antagonize glucocorticoid-induced osteoporosis by inhibiting ferritinophagy with resultant limited ferroptosis of osteoblasts