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Although it could be anticipated that the magnitude of glutathione increases would correlate with behavioral improvements as in other studies ( When examining the relationship between baseline glutathione levels, the responders ( n = 12) had significantly higher baseline concentrations of both total and reduced glutathione than baseline and non-responders ( n = 8)

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If disrupted, permeation of potentially noxious molecules and organisms from the intestinal lumen can result in a cascade of events including immune activation and inflammation, eventually triggering the development of intestinal and systemic diseases (Fig