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Based on the results obtained in the wet lab and in silico, they hypothesized that VIT-E inhibits LPx by reducing ROS and by increasing enzymatic antioxidant defense through binding of KEAP1, thus interfering with the NRF2-KEAP1 proteinprotein interaction and leading to ARE activation

Diabetes mellitus refers to metabolic diseases which are characterized by hyperglycemia that develops as a result of impairment in insulin secretion, insulin action, or both [5, 6]

However, cardiac tissue is particularly vulnerable due to its high energy demands, unique metabolic characteristics (such as high mitochondrial density and continuous oxidative stress), and its critical role in physiological functions (20)

Thoracoscopic Robotic or Open Lobectomy for Lung Cancer (TROLL)

Diminished levels of glutathione have always been associated with aging