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Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis

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Administration: Intramuscular (IM) injections are commonly used

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A broad panel of antibodies was employed, including those for FOXO4, p53, phospho-p53, p21, p16, cleaved-Caspase3, BAX, BCL-2, testosterone synthesis enzymes (3-HSD, CYP11A1, CYP17A1), and various SASP factors (IL-1, IL-6, TNF-, TGF-)