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Cell 179 , 11441159.e1115 (2019)

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Real-world data suggests comparable weight loss outcomes between oral and injectable semaglutide when doses are optimized, though individual results vary more with oral formulations

Nevertheless, if its senolytic action has been demonstrated in several diseases such as osteoarthritis 15,16 as well as in neurodegenerative diseases 17 , the effect of ABT-263 is restricted to senescent cells from specific cell types 18 , leading to the necessity to identify new potential senolytics to target senescent cells in age-related diseases