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[13] By 2006, Konynenburg had developed and presented what is now known as Rich's Protocol

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This makes it especially relevant for longevity-focused patients

Because a major physiologic function of GSH is to provide cells with a reducing environment and to destroy the reactive oxygen compounds and free radicals formed in metabolism, organs that have low concentrations of other antioxidants (such as catalase and superoxide dismutase) are thought to be more dependent on GSH for detoxification of reactive oxygen species than are organs that have alternative antioxidants