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In theory with ideal, healthy intestinal flora these bacteria will produce a portion of the required B12

The observation on the release of zinc from brain tissue during activity published in Nature in 1984 [218] provided initial evidence that transition metals could be directly involved in signalling [112, 134, 219,220,221,222,223,224,225,226,227,228,229]

The insignificant sequence and period effects confirm that there were no carry-over effects, indicating a sufficient washout period between challenge weeks

None of these interactions is a reason to avoid the supplements outright, but they are good reasons to involve a clinician

Bounous G, Gold P (agosto de 1991)