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The combination covers four distinct but functionally overlapping pathway systems inflammation, matrix remodeling, angiogenesis, and cellular migration in a single-preparation research format

Expending the known reduced species (NADH+, reduced glutathione, etc.) to neutralize the deleterious compounds weakens the organisms capacity to combat further oxidative stress

When glutathione is depleted, the mitochondria sustain physical damage from their own energy production processes, leading to a catastrophic drop in ATP output

It also can result in common Hashimotos triggers, including food sensitivities (many with Hashimotos are sensitive to gluten, dairy, and/or soy) and less resistance to pathogenic invasions (which can further impact nutrient absorption, becoming a vicious cycle)

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