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In the last decade, it was evident that genetic and pharmacological inhibition of mTORC1 prolongs lifespan and delays aging, but that inhibition of mTORC2 negatively affects mammalian health and lifespan and leads to many side effects of rapamycin [39]

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Polymorphic variants of genes encoding MTHFR, MTR, and MTHFD1 and the risk of depression in postmenopausal women in Poland