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Elferink and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

The 2 mL reconstitution is generally preferred by researchers because the larger injection volume reduces the risk of dosing error, spreads the depot over a slightly wider subcutaneous footprint, and the 40 IU mark sits in the well-graduated middle of the U100 scale

For in vivo or ex vivo studies (if employed in nonclinical contexts), consider potential biodistribution, clearance, and off-target interactions in experimental design

ACS Omega , 10 (5), 44274441

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