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Since the reason for the lower body fat mass in LepR GHR KO mice is unknown, we believe that it is likely related to a larger number of cells affected by GHR deletion, including peripheral cells that also express the LepR

Strikingly, in the active structure of the c-MET/HGF dimeric complex, only HGF I simultaneously recruits two c-METs by using two distinct surfaces localized on the opposite sides of this HGF (Fig

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In a high-cholesterol diet-fed ApoE / mouse model of atherosclerosis, P-Mn/TI@mHSA enhanced both plaque targeting and inward diffusion within plaques

It also helps protect against oxidative stress by conjugating to GSH, neutralizing free radicals