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For instance, a study reported no significant association between C677T and bipolar disorder 64 , while another study found no evidence for C677T genotypic or allelic association with BD regardless of type I or II 65

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Renal Failure

In the current study, post-weaning exposure to MSG exhibited marked depletion in the levels of brain monoamines (DA, NE and 5-HT), as well as remarkable increment in glutamate levels, which were coupled with marked alterations in spatial working memory and locomotor activity demonstrated by reduction in cognitive function in Y-maze test and prolongation in latency time in OFT, respectively, compared to normal control group