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[3] Yokoyama H., et al

Semaglutide produced less weight loss than tirzepatide head-to-head, about 14% versus 20%. Its body-composition substudy measured a roughly 62:38 fat-to-lean loss split by mass, compared with about 75:25 for tirzepatide in a separate trial. The scan overstates muscle loss because lean mass includes water and organ tissue

doi: 10.4137/CMED.S38201 12 HarveyS

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Quercetin stimulates AMPK activity in skeletal muscle cells to activate Akt and GLUT4 membrane receptors, facilitating glucose diffusion and metabolism [87]