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Low levels of B12 can contribute to irritability, depression, or mood swings

Seek Care When Needed Severe symptoms, chest pain, shortness of breath, fainting, allergic reactions, neurologic symptoms, or acute illness require medical care

This enzyme catalyzes the N-methylation of nicotinamide using S-adenosyl-L-methionine (SAM) as a methyl donor, effectively creating a "metabolic drain" that depletes both NAD+ precursors and cellular methylation capacity

The term pernicious means harmful, and pernicious anemia causes harm to several body systems: Pernicious anemia typically affects people aged 60 to 80 of Northern European descent