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Arch Toxicol 86(11):16491665 Mats JM, Segura JA, Alonso FJ, Mrquez J (2012b) Sulphur-containing non enzymatic antioxidants: therapeutic tools against cancer

J., Ezzati, M., Alonso-Alconada, D., Hausenloy, D

This dual functionality establishes it as a complex yet promising target for cancer treatment (216)

doi: 10.3390/nu13030856 90 HouYGuDPengJJiangKLiZShiJet al

In summary, there remain three bottlenecks for clinical breakthroughs, as follows, the low bioavailability of natural products should be improved, the combined application of two or more compounds should be investigated for more prominent pharmacological effects and the evidence of clinical efficacy of other compounds requiring further confirmation