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Among these compounds, compound 5 (Figure 8) exhibited the most promising cytoprotective efficacy against oxygen-glucose deprivation/reoxygenation-induced injury in BV2 microglial cells

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Neuroprotective Properties Under Investigation The Zagreb groups 2016 review in Current Neuropharmacology described peripheral BPC-157 administration altering serotonin synthesis rates in specific brain regions, particularly nigrostriatal and other dopaminergic pathways (Tohyama, Sikiric, Diksic, 2004, Life Sciences )

FDA described insufficient clinical safety information, characterisation concerns and inadequate evidence of effectiveness for its reviewed use

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