The risk of magnesium deficiency is higher in those who are heavy alcohol users, of older age, have type 2 diabetes and other medical conditions, and have used certain acid reflux medications long-term, like omeprazole
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Similarly, total oxidative status (TOS), oxidative stress index (OSI), and urinary 8-isoprostane levels (a non-enzymatic peroxidation product of arachidonic acid) tend to increase after extended or continuous NSW, with concurrent decreases or alterations in total antioxidant capacity (TAC) and total antioxidant status (TAS), highlighting an imbalance in favor of oxidative damage 74,75,76,77