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Typical use ranges from 250 to 650 mg, depending on your goal

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It must be stored in the refrigerator (2C to 8C or 36F to 46F) and typically used within 1428 days

extreme caloric restriction may exacerbate menstrual irregularities Micronutrient optimization: Maintain adequate iron intake, particularly if experiencing heavier menstrual bleeding Contraceptive considerations: Discuss alternative contraceptive methods with your provider, as tirzepatide may affect oral contraceptive absorption For women with pre-existing menstrual irregularities or PCOS, tirzepatide treatment may ultimately improve cycle regularity as metabolic parameters normalize