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doi: 10.1016/j.ijpharm.2008.08.047

Salt, pH, mucus, and tissue damage can all shift how a peptide behaves once it is in the body

5.2 Oxidative stress-related eye diseases Imbalance of prooxidant-antioxidant reactions leads to damage of nucleic acids, proteins and lipids, which produce chronic inflammation and loss of tissue function

Many studies have noted that because glutathione can relieve the toxicity associated with NAPQI (178), fasting before acetaminophen administration maintains baseline levels of glutathione in all animals, which increases the consistency of experimental results and the success of acetaminophen-induced liver failure