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When produced excessively, it may suppress the release of Thyroid Stimulating Hormone from the pituitary. 18 It also forces T4 to be converted to reverse T3 (rT3) which actually blocks thyroid function, even though thyroxine levels look adequate when tested. 19 Blood glucose imbalance also triggers cortisol secretion, and insulin resistance may have a direct negative effect on the thyroid, too

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Your provider should use this information alongside clinical assessment and biomarkers to guide personalized recommendations

Meki ARMA.El-OmarH

Berberine Pharmacology and the Gut Microbiota: A Review of the Mechanisms of Action and Clinical Implications