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albicans achieves stable commensal colonization on healthy oral, esophageal, vulvovaginal and other mucosal epithelial surfaces by regulating the expression of adhesins and virulence factors, adapting to the nutrient-poor microenvironment of mucosae, and evading host immune surveillance with the synergistic effect of the resident microbiota that competes for nutrients and restricts its overgrowth (Schille et al., 2025)

For metabolite clustering analysis, average linkage hierarchical clustering was performed in the Statistical Analysis module of MetaboAnalyst 6.0 using Euclidian distance as a similarity metric

The structure and function of the cells change and begin to differentiate as they move up through the epidermal layers

No antimicrobial peptides were detected in the proteomic data (Supplementary Fig