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Any use outside of a regulated clinical trial setting carries significant and unpredictable risks

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In rat embryonic myocytes with hypoxia/reoxygenation, trimetazidine pre-treatment mitigated the increase in oxidative stress proteins such as lactate dehydrogenase and ROS [169]

Likewise, pairing antioxidants with kinase inhibitors, such as sorafenib or lenvatinib, may alleviate oxidative injury and delay drug resistance mediated by ferroptosis or mitochondrial dysfunction [144]

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