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None of them are proven, said Dr

This degree of metal-sensing promiscuity across a collection of closely related ZntRs in a cell is not only anticipated but may well be beneficial, since it is well documented that the P 1B-2 ATPase, ZntA, can efficiently transport a range of divalent soft transition metal ions, including Zn II , Cd II , Pb II and Hg II by adopting a range of coordination geometries in the transmembrane metal binding site (Section 5.3.1)

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The purine component in NAD + is adenine, which is incorporated from ATP 23