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It is generally used for 3 months before considering a surgical referral, the latter performed for cosmetic reasons and only in stable cirrhosis patients after weighing risk to benefit ratio (96, 97)

About Isotretinoin Treatment Isotretinoin (Aknetrent) is an oral medication that shows extremely high efficacy for severe and treatment-resistant acne that doesnt respond to conventional dermatological treatments

Individuals considering extended protocols should discuss this temporal limitation with healthcare providers and maintain appropriate monitoring throughout treatment

PMC 34748