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In addition to replicating these results in larger samples, future studies should more closely examine treatment-related glutamate elevations and GABA reductions as potential biomarkers of successful AUD treatment response as this may generalize across interventions

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We acknowledge Diamond Light Source for access and support of the cryo-EM facilities at the UKs national Electron Bio-imaging Centre (eBIC), instrument eBIC Titan Krios IV [under proposal EM20223-37], funded by the Wellcome Trust, MRC and BBRSC

Is a 10-day stay with a structured Day 7 feedback session built into the process

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