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doi: 10.1016/j.cub.2021.08.032 127 XuT.ZhangN.XuM.GlauserG.TurlingsT

doi: 10.1523/JNEUROSCI.3306-14.2015 85 GarretsonJTSzymanskiLASchwartzGJXueBRyuVBartnessTJ

PPARa contributes to neuronal ferroptosis by regulating the FSP1-CoQ10-NAD(P)H pathway through its transcriptional activity To elucidate the specific mechanism by which PPARa regulates FSP1, we constructed stable cell lines with either over-expression or knockdown of PPARa using lentiviral vectors

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Its most prominent function has been suggested to regulate apoptosis in senescent cells