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median observation time of 49 months for the second) were able to provide valuable information on its natural history, estimate the sample size needed for statistically powerful clinical trials, and conclude on the patients/diseases characteristics that correlate more with disease progression [243, 244]

Results of experimental and clinical investigations demonstrated the effects of the synthetic peptide on the course of retinitis pigmentosa, a degenerative process of the retina resulting from disturbed metabolism of specific proteins in the pigmented epithelium and other retinal layers [38]

Reference data only not a recommendation

This is the kind of breakdown we use internally when advising research partners

Jul 2012;97(7):1008-1013