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At least six industry-independent intervention studies based on 17 to 40 conventional tobacco users have been conducted to evaluate the acute effects of HTP use on selected cardiovascular outcomes in humans

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2 Luke Krneta, New Pitch Redirects His Career, Pittsburgh Press , April 26, 1992: D6

The Government has missed the opportunity to disallow any new variant names or to limit the market to those brand and variant names that existed when the legislation was first introduced