The mechanistic research in this area has connected the compounds activity to copper-dependent angiogenic factors and to its broader gene expression effects on cellular proliferation and ECM remodeling
For GSH assay, cells were treated in Earles balanced salt solution (EBSS), supplemented with 25 mM glucose, 4 mM glutamine, 1 X MEM vitamin solution (Life technologies, CA, USA), 0.22% wt/vol NaHCO 3 , 1 mM sodium pyruvate, 0.2% BSA, 25 mM HEPES, 100 U/ml penicillin and 100 g/ml streptomycin in the presence or absence of 1 X MEM amino acid solution (Gibco, CA, USA) with or without 100 M cystine
[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Joseph P., Leong D., McKee M., Anand S.S., Schwalm J.D., Teo K., Mente A., Yusuf S
Apports nutritionnels et hygine de vie Pour favoriser la production naturelle de glutathion, privilgiez une alimentation riche en acides amins soufrs : brocoli, ail, oignon, ufs, pinards, avocats
The GSH levels were 73.1 74.1 and 669.1 339.5 mol/l in each low and high group (Table 1)