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It was found that approximately 10% of BA patients showed serum CMV IgM+, and CMV IgM + BA patients usually have a worse outcome with reduced clearance of jaundice, native liver survival, and increased mortality, representing a distinct clinical and pathological entity of BA with a diminished response to KPE (74, 75)

Patients should be advised not to take ascorbic acid, vitamin C supplements along with deferoxamine chelation therapy unless such supplements are prescribed with the approval of their health care professional

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We also propose several new promising approaches to improve anti-angiogenic efficacy and provide a perspective for the development and research of anti-angiogenic therapy

Another study evaluated the bioavailability of total polyphenols from coffee silver skin extract using simulated gastrointestinal digestion and colonic fermentation (117)