In diet-induced obese mice (16 weeks HFD), subcutaneous 5-Amino-1MQ treatment for 11 days (20 mg/kg/injection, three injections daily) produced significantly reduced body weights, white adipose tissue masses, and adipocyte cell sizes compared to vehicle controls
[DOI] [PMC free article] [PubMed] [Google Scholar] 71.Mancini A., Milardi D., Bianchi A., Festa R., Silvestrini A., De Marinis L., Pontecorvi A., Meucci E
Molecular Weight: 1593.76 g/mol
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Flippase is an enzyme active under basal conditions that shifts PS from the outer to the inner membrane leaflet, thereby preventing PS exposure