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Neurochem Res 9: 15991614

As AD progresses, this diminished uptake of glucose becomes increasingly apparent in regions such as the hippocampus, parietal cortex, cingulate cortex, and temporal cortex [161, 162]

Metabolic adaptation

(3) Iron homeostasis modulation: iron chelation with deferoxamine (DFO) and inhibition of NCOA4dependent ferritinophagy are illustrated as means to lower the labile iron pool and reduce ironcatalyzed lipid peroxidation