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In a 6-month, randomized, double-masked, placebo-controlled study, ruboxistaurin enhanced skin microvascular blood flow at the distal calf, reduced sensory symptoms, improved the quality of life, and was well tolerated in DPN patients

These low nutrient levels can lead to symptoms like fatigue and brain fog

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Additionally, the suspended particles continue to adhere to the lid margins, fornices, and the epithelial defect area

Low glutathione levels can also manifest in the skin, causing it to become dry and flaky