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Consequently, this paper aims to comprehensively address the innovative concept of intra-articular PBM for KOA for the first time

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Epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea, has been reported to promote osteogenesis by upregulating Runx2 and Osterix while concurrently suppressing osteoclastogenesis via inhibition of the RANKL/NF-B signaling axis (Lin et al., 2018)

Thus, vitamin C can react with and regenerate the radical of vitamin E