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Further experimental studies suggest that KGDHC not only limits the rate of NADH production and substrate-level phosphorylation, but is also a source of ROS in mitochondria [80]

Docosahexaenoic acid inhibition of inflammation is partially via cross-talk between Nrf2/heme oxygenase 1 and IKK/NF-B pathways

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Indeed, as the glutathionylated moiety is hydrophilic, the conjugate cannot usually simply re-diffuse back into the cell [77]

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinasemediated suppression of histone deacetylase 2