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Oncogenic KRAS drives tumorigenesis by promoting fatty acid biosynthesis [92], upregulating ACSL3 to reprogram lipid homeostasis [93], and inducing NRF2 expression to activate the antioxidant system [94]

Metformin enhances mitochondrial biogenesis and thermogenesis in brown adipocytes of mice

Nicotinamide phosphoribosyltransferase/sirtuin 1 pathway is involved in human immunodeficiency virus type 1 Tat-mediated long terminal repeat transactivation

BER enzymes are primarily targeted at removing N7-MeG and N3-MeA lesions, subsequently repairing the DNA through the collaborative action of DNA polymerase and DNA ligase, thus restoring the DNA strand to its original, non-damaged state [165]

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