Disclosure of interest: Khudayarova S.M.:nothing to disclose, Rakhmatullayeva G.K.: nothing to disclose E-Posters - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.02 - SECONDARY PREVENTION P2555 - ESOC25-2084 AN EVALUATION OF MEDICAL MANAGEMENT FOR SECONDARY PREVENTION OF ISCHAEMIC STROKE IN A TERTIARY STROKE CENTRE Nicole Cosgrave 1,2 , Basmah Karembaks 1 , Vanessa Farnan 1,2 , Anne-Marie Liddy 2 , Rory Durcan 2 , Karl Boyle 2 , David Williams 1,2 1 Department of Medicine, RCSI University of Medicine and Health Sciences, Dublin, Ireland, 2 Department of Geriatrics and Stroke Medicine, Beaumont Hospital, Dublin, Ireland Background and Aims: Recurrent ischaemic strokes occur in 9-15% of patients within one year

Because cellular damage of endothelial cells exposed to homocysteine may be prevented by pretreatment of cells with catalase, which allows the detoxification of hydrogen peroxide that freely crosses the cell membrane (Starkebaum and Harlan, 1986
TB500 is a 43-amino-acid peptide that enhances cellular migration, reduces inflammation, and promotes new blood vessel formation
The skin, in particular, has its own antioxidant defense system that eliminates excess ROS through both enzymatic and non-enzymatic pathways, thereby maintaining redox balance and prevent the damage of ROS to cellular tissues ( Although ROS contribute to oxidative stress and inflammation, they are also essential for normal physiological functions
Both moderate and high-intensity exercises can enhance glutathione synthesis, though overtraining without proper recovery may have the opposite effect[16]