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8 No thyroid dysfunction was detected after 24 weeks (mean follow-up period: 317 210 days in the pembrolizumab group and 346 362 days in the nivolumab group)

Additionally, a difference was observed between the two monomers in the holo form: monomer B had lower RMSF values (S2B Fig)

Thymosin 4s core molecular function is well established: it sequesters monomeric G-actin, binding it roughly 1:1 and regulating the balance between free actin and the polymerized filaments that drive cell shape and movement

TABLE 3 The comparison of primary outcome between two groups