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Solid tumors, such as osteosarcoma, generally suffer from an inadequate oxygen supply due to the rapid proliferation of cancer cells, incomplete vascularization, and uneven distribution
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Nevertheless, as an effective antioxidant, the overexpression of GSH in tumor cells is one of the typical reasons for reducing free radicals, and consequently contributing to radiation resistance (Xie et al., 2019)
This peculiar situation, in which Te is abundant in human food but scarce in soil, suggests that plants have evolved highly efficient mechanisms for absorbing Te through their roots compared to other trace elements [26]
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