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Representative experimental areas include: Metabolic disease and obesity: Murine models show that MOTS-C improves insulin sensitivity, enhances skeletal muscle glucose uptake, promotes lipid utilization, and reduces dietinduced obesity while improving glucose tolerance

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Arbaclofen, the R-enantiomer of baclofen, has been shown to significantly reduce repetitive grooming behaviors in Fmr1 knockout mice following acute injection, and systemic treatment improved sensory filtering abilities in Cntnap2 knockout rats, suppressing excessive acoustic startle responses (146)

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